https://gbucci.r-universe.devRecent package updates in gbucciR-universehttps://github.com/gbucci.pnghttps://gbucci.r-universe.devTue, 28 Apr 2026 13:07:19 GMTbucci.g@gmail.com (Gabriele Bucci)ClonalSim generates realistic mutational profiles of tumor samples with hierarchical clonal structure. It simulates founder, shared, and private mutations with biologically realistic noise models including intra-tumor heterogeneity (Beta distribution) and technical sequencing noise (negative binomial depth variation, binomial read sampling, base errors). The package is designed for benchmarking variant callers, testing clonal deconvolution algorithms, and teaching tumor heterogeneity concepts.https://github.com/r-universe/bioc/actions/runs/38073470306Tue, 28 Apr 2026 13:07:19 GMTClonalSim1.1.0successhttps://bioc.r-universe.devhttps://github.com/bioc/ClonalSimIntroduction_to_ClonalSim.RmdIntroduction_to_ClonalSim.htmlIntroduction to ClonalSim2025-10-29 13:01:112026-04-21 14:52:30